Mysimba Tablets for weight loss

Mysimba pills are prescription-only and contain a combination of 2 active ingredients, naltrexone and bupropion, which help support weight loss. Up to 4 tablets are taken every day, increasing during your first 4 weeks of treatment.

What is Mysimba used for?

Mysimba prescriptions are given to help weight loss in adults who are overweight. This means people who are over 18 years old and have a BMI of over 30, or over 27 if they have weight-related health conditions like high blood pressure or high cholesterol.

Our doctors will take your BMI and all of your medical history into consideration and may prescribe off-label when making a decision about treatment.

Scientists don’t fully understand exactly how Mysimba works, but the active ingredients affect the part of the brain that controls appetite and energy levels. This helps support weight loss in 2 ways:

• reducing a person’s appetite so they find it easier to stick to a diet
• increasing the amount of energy their body uses up, speeding up weight loss

The effect Mysimba has on suppressing appetite and increasing energy usage doesn't cause weight loss on its own. The medication only works effectively alongside a healthy diet and exercise plan, increasing how much weight you lose.

What are the ingredients in Mysimba?

Mysimba diet pills contain 2 active ingredients: naltrexone and bupropion. Both of these Mysimba ingredients work differently but help to support weight loss when taken in combination.

You can buy Mysimba online using services like Asda Online Doctor, which allow you to order prescription treatments remotely. You can also order repeat prescriptions online from the NHS if you’re already receiving treatment.

How to buy Mysimba tablets with Asda

Ordering Mysimba from Asda Online doctor is simple, just follow these steps:

1. start a quick online assessment
2. answer questions about your health
3. sign in or create an account
4. place your order
5. one of our doctors will check your assessment
6. if Mysimba is right for you, your order will be approved
7. your order will be sent direct to you or to a local Asda pharmacy for collection

Our online weight loss service offers:

• no need for face-to-face consultations
• no need to travel for consultations or medication unless you want to click and collect
• free delivery as standard
• refunds on all orders that can’t be approved
• ongoing care provided by online doctor direct messaging through your patient account

When you start treatment via Asda Online Doctor, we provide you with a free support package that our in-house nutritionists have developed together with our doctors. In addition to detailed tips on nutrition and exercise, this also includes templates for trackers and plans to help you more easily organise your weight loss journey.

If you have any concerns during your treatment, you can check out our Weight Loss Service FAQ for quick answers to common questions our patients ask us.

Mysimba are oral tablets which means they need to be swallowed. You should take them whole, without crushing or cutting them and use water to help you swallow them if needed.

It’s important to take Mysimba as advised by your doctor. That means the right number of pills at the right times.

The recommended Mysimba dosage changes during the first 4 weeks of your treatment. The recommended starting Mysimba dose is one tablet once a day. The recommended maintenance dose you take from week 4 onwards is two tablets twice a day.

Mysimba does come with some health risks and possible side effects like all medications. But, Mysimba should be safe for you as long as treatment has been approved by a doctor.

“Blood pressure and pulse should be measured before starting treatment with Mysimba and should be checked regularly while taking it. We would recommend at least weekly checks, especially if you already have a diagnosis of high blood pressure. If your blood pressure or pulse is consistently raised, you should stop taking Mysimba.” - Dr Babak Ashrafi, Clinical Lead for Service Expansion at ZAVA

There are some medications or health conditions that might make Mysimba unsafe, but a doctor will always check these before approving treatment. In the case of Asda Online Doctor, these are covered in the order assessment.

See the ‘Mysimba contraindications’ and ‘Mysimba interactions’ sections for more information on other medications and health conditions that affect how safe Mysimba is.

Mysimba side effects can be quite varied, but most common side effects are mild and can go away shortly after starting treatment (usually within a few days).

Very common side effects of Mysimba affect more than 10% of people who take it and include:

• feeling sick or throwing up
• getting constipation
• headaches

Common side effects of Mysimba affect up to 10% of people who take it and include:

• feeling anxious
• feeling dizzy
• feeling shaky
• having trouble sleeping
• food tasting different
• having trouble concentrating
• feeling tired or weak
• hearing a ringing in your ears
• having a fast or irregular heartbeat
• getting hot flushes
• high blood pressure
• pain around the stomach
• sweating more than normal
• feeling itchy or getting a rash
• hair loss
• feeling irritable
• feeling jittery

For full information on all possible side effects, see the Mysimba patient information leaflet.

Get medical help right away if you any signs of serious side effects, including:

• depression or suicidal thoughts
• fits or seizures
• red itchy spots starting on your arms and legs or blisters and bleeding around the mouth, eyes, nose or genitals
• intense muscle cramps or pain
• a butterfly shaped rash on your cheeks and nose or other skin rashes or lesions
• agitation, hallucinations, coma, high temperature, unstable blood pressure, jerky reflexes, stiff muscles or serious stomach problems, if you’re taking antidepressants

Mysimba isn’t a suitable treatment for everyone. There are some other medications (drug interactions) and preexisting health conditions (contraindications) that can make Mysimba unsafe to take.

A doctor will check these before prescribing treatment so make sure to give accurate information during your consultation or assessment.

Mysimba contraindications

Mysimba is not suitable for people who:

• are allergic to the ingredients
• have uncontrolled high blood pressure
• have a history of fits
• have a current brain tumour
• are a heavy drinker
• have bipolar disorder
• have a history of eating disorders
• have severe liver disease
• have end-stage kidney disease

Mysimba interactions

You shouldn’t take Mysimba with:

• medications used to treat Parkinson’s, like phenelzine, selegiline or rasagiline
• medications containing opiates, like dextromethorphan, codeine, methadone, morphine or paregoric

There are also many medications that can increase your risk of side effects when taking Mysimba, including medications:

• that increase your risk of fits
• for treating depression
• for treating high blood pressure
• for treating irregular heart beat
• for treating cancer
• for treating Parkinson’s
• for treating heart disease or stroke
• for treating HIV and AIDS
• for treating epilepsy

Mysimba is not the only weight loss medication available on the market. There are a range of Mysimba alternatives available to consider, including:

• Wegovy
• Mounjaro
• Saxenda
• Orlistat
• Phentermine

These treatments contain different active ingredients and vary based on who they are suitable for and their availability in the UK.