TriRegol

When do I start taking TriRegol?

You should start taking TriRegol on the first day of your period so you can protect yourself from pregnancy straight away.

If it’s your first pack of TriRegol and you start between the second and fifth day of your period, you should use condoms for protection for the first 7 days.

• You should take 1 TriRegol pill at the same time each day. Use the numbers, colours and arrows on the blister strip to help you take the pills in the right order. Each TriRegol blister strip has 21 pills and there are 3 different colours of pills.
• You start with 1 pink pill per day for 6 days, then 1 white pill per day for the next 5 days and then 1 yellow (ochre) tablet per day for the final 10 days.
• After you have taken all 21 pills, you will have a 7 day break. During this week, you might have some withdrawal bleeding and you will still be protected from pregnancy.
• Once your 7 day break is over, start taking your next strip of 21 TriRegol pills.

If you take a TriRegol pill and vomit or have diarrhoea within 4 hours, you might not be protected from pregnancy. You should keep taking your pills as normal and use condoms for the next 7 days.

What do I do if I forget to take TriRegol?

If you forget to take a TriRegol pill within 12 hours or less:

• take your TriRegol pill as soon as you remember. You will still be protected from pregnancy.

If you forget to take 1 TriRegol pill more than 12 hours late in the first week:

• take your TriRegol pill as soon as you remember, which might mean taking 2 pills on the same day. You should use condoms for the next 7 days

If you have missed 2 pills or more and had unprotected sex in the past 7 days, you might need to use emergency contraception. Speak to your doctor or pharmacist for more advice.

If you forget to take 1 TriRegol pill more than 12 hours late in the second week:

• take your TriRegol pill as soon as you remember, which might mean taking 2 pills on the same day. You do not need to use condoms for extra protection

If you have missed 2 pills or more and had unprotected sex in the past 7 days, you might need to use emergency contraception. Speak to your doctor or pharmacist for more advice.

If you forget to take a TriRegol pill more than 12 hours late in the third week:

• take your TriRegol pill as soon as you remember, which might mean taking 2 pills on the same day. Keep taking your pill each day
• skip your 7 day break and start your next strip of pills straight away

If you are unsure about what to do, speak to your doctor or pharmacist for advice.

What do I do if I take TriRegol twice?

If you take TriRegol twice, you might feel sick or vomit. You could also have some vaginal bleeding. It’s best if you speak to a healthcare professional, like your doctor or pharmacist, straight away.

Can pregnant or breastfeeding women take TriRegol?

You should not take TriRegol if you are pregnant. If you think you might be pregnant, stop taking TriRegol and use another method of contraception until you speak to your doctor.

If you are breastfeeding, you might be able to use TriRegol, but this will depend on when you gave birth. Your doctor might recommend you take a progesterone only pill as an alternative contraception.

What should I watch out for if I want to stop taking TriRegol?

When you stop taking TriRegol, you may have some withdrawal bleeding. If you don’t want to get pregnant, you need to use another method of contraception, such as condoms.

You might get side effects when you take TriRegol and you can speak to your doctor at any time for advice on what to do.

Common side effects of TriRegol are:

• acne
• headaches
• mood swings
• vomiting
• weight gain
• breast tenderness or breast pain
• chloasma (yellow or brown patches on the skin)

Less common side effects of TriRegol are:

• change in sex drive
• migraines
• vomiting or diarrhoea
• fluid retention
• high blood pressure
• breast enlargement

Rare side effects of TriRegol are:

• hearing problems (otosclerosis)
• high levels of fat in the blood (hyperlipidaemia)
• weight loss
• vaginal discharge
• liver function problems
• ulcerative colitis
• breast cancer or cancer of the cervix

You can report any side effects using the MHRA Yellow Card Scheme in the Google Play or Apple App Store.

Does the risk of thrombosis increase?

You are slightly more likely to have a blood clot when taking TriRegol because it contains oestrogen.

Blood clots can occur in your:

• legs (deep vein thrombosis)
• lungs (pulmonary oedema)
• heart (heart attack)
• brain (stroke)

Stop taking TriRegol and call 999 if you notice any signs of blood clots such as:

• feeling short of breath
• chest pain
• blurry vision
• swelling in your calf

TriRegol pills can interact with medicines and this may reduce your protection against pregnancy.

Speak to your doctor or pharmacist if you are taking any of the following:

• epilepsy medication such as primidone, carbamazepine, phenytoin or topiramate
• barbiturates such as phenobarbital
• any products containing St. John’s wort
• ritonavir for HIV treatment
• hepatitis C treatments such as ombitasvir or dasabuvir
• antifungal medicines such as griseofulvin
• antibiotics such as ampicillin, tetracycline or rifampicin
• tricyclic antidepressants such as amitriptyline or imipramine
• ciclosporin

TriRegol may not be suitable for you if you are taking the above medication. Your doctor may advise you to take a different contraceptive or use additional contraception such as condoms.

The active ingredients in TriRegol are:

• each pink pill contains ethinylestradiol 30mcg and levonorgestrel 50mcg
• each white pill contains ethinylestradiol 40mcg and levonorgestrel 75mcg
• each yellow (ochre) pill contains ethinylestradiol 30mcg and levonorgestrel 125mcg

The other ingredients in all 3 TriRegol pills are: colloidal anhydrous silica, magnesium stearate, talc, maize starch, lactose monohydrate, carmellose sodium, povidone K30, macrogol, copovidone, calcium carbonate, sucrose, titanium dioxide (E171)

Other ingredients in pink pills only: red iron oxide (E172)

Other ingredients in yellow (ochre) pills only: yellow iron oxide (E172)

If you have an allergy or hypersensitivity to any of these ingredients, please speak to your doctor for advice before taking TriRegol.

How should TriRegol be stored?

You should store TriRegol in its original pack, below 25°C and away from sunlight and moisture. Keep TriRegol in a safe space away from children and pets.

How must TriRegol be disposed of?

Dispose of your TriRegol pills at your nearby pharmacy. You should not throw away TriRegol pills in your bin or down the drain at home, even if they are expired.

What does TriRegol look like?

Each blister strip of TriRegol contains 21 round pills:

• 6 pink pills
• 5 white pills
• 10 yellow (ochre) pills

In which pack sizes is TriRegol available?

TriRegol pills are available in pack sizes of 1, 3, 6, and 13 blister strips. Each TriRegol blister strip contains 21 pills.

Information on the manufacturer

The company that holds the marketing authorisation of TriRegol is Gedeon Richter Plc, Gyömrői Út 12-21, 1103 Budapest, Hungary.

TriRegol is manufactured by Gedeon Richter Plc and distributed by Consilient Health (UK) Ltd, No.1 Church Road, Richmond upon Thames, Surrey, TW9 2QE.