Epiduo Gel

Epiduo gel is an antibiotic-free acne treatment. With 2 active ingredients, Epiduo gel can help clear your skin within 6 to 8 weeks.

Front of box containing 45g of Epiduo 0.1%/2.5% gel
Side of box containing 45g of Epiduo 0.1%/2.5% gel
Tube containing 45g of Epiduo 0.1%/2.5% gel
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Prices from £34.50

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45 g - £34.50


What is Epiduo gel and what is it used for?

Epiduo gel is a gel you apply onto your skin to treat acne. It is used on its own to treat mild to moderate acne, or in combination with oral antibiotics for more severe acne.

Acne can appear as spots, blackheads or whiteheads on your skin. If you get hard lumps which are painful or deep under your skin, you may need a different type of acne treatment.

How Epiduo gel works

Epiduo gel works by using small amounts of adapalene (0.1%) and benzoyl peroxide (2.5%) daily to gently treat acne on your skin.

The adapalene in Epiduo gel is a type of retinoid. Using adapalene reduces the inflammation associated with acne and helps to unblock pores by clearing dead skin cells.

Benzoyl peroxide works by softening the outer layer of your skin to remove dead skin cells. As an antimicrobial agent, benzoyl peroxide also kills off bacteria that cause acne on your skin.

How to use Epiduo gel

To use Epiduo gel, you need to follow these steps:

  1. At night, use a cleanser to wash your face and remove any makeup before you apply Epiduo gel. Gently pat your face dry with a clean towel.
  2. Take the cap off the Epiduo gel pump and press the top to release 1 or 2 pumps of gel. On the pump, write the date if it is the first time you are opening it.
  3. Apply a thin layer of Epiduo gel by spreading it evenly over the affected areas of skin on your face. Avoid getting Epiduo gel too close to your eyes, nostrils or lips.
  4. Wash your hands after applying Epiduo gel.

If Epiduo gel gets into your eyes, mouth or nostrils, you should wash these areas straight away with warm water.

Epiduo gel might cause your skin to break out the first few times you use it. This is normal and should not last long before you start to see your acne improve.

If you find Epiduo gel is irritating your skin after you use it, you can try:

  • applying less gel
  • using the gel less often
  • using an oil-free moisturiser after you apply it

Epiduo gel lifestyle tips

  • Epiduo gel can bleach fabric or hair, so keep your hair and clothes away from your face after you apply it.
  • Wait for your skin to absorb Epiduo gel before you go to sleep to avoid transferring it onto your pillow or bed sheets.
  • Wear a hat and sunscreen when you go outdoors to protect your face from sunburn.
  • Avoid applying Epiduo gel in the morning as you are more likely to get sun damage.
  • Alongside Epiduogel, use non-comedogenic makeup, cleansers and moisturisers to stop acne coming back.
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Medically reviewed by:
Dr Kathryn Basford

Dr Kathryn Basford is a qualified GP who works as a GP in London, as well as with ZAVA. She graduated from the University of Manchester and completed her GP training through Whipps Cross Hospital in London.

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Article created: 13 Oct 2021

Last reviewed: 13 Oct 2021


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Asda Online Doctor by ZAVA offers a range of options to manage acne symptoms, including antibiotics, anti-inflammatories for inflamed skin, and combination treatments that include Zinc to help skin repair.

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