Hezkue spray

Hezkue spray is a type of prescription erectile dysfunction treatment that comes as a mouth spray. It’s sprayed onto the tongue and then swallowed. The standard dose is 4 pumps, which provides 50mg of the active ingredient sildenafil. This is the same ingredient in the well-known ‘little blue pill’ called Viagra, and in generic sildenafil tablets as well.

It may be a suitable alternative if you do not like or struggle to swallow tablets. The spray also contains peppermint to make the flavour more appealing.

Hezkue spray contains sildenafil, which is a phosphodiesterase type 5 (PDE-5) inhibitor. This type of medication works by stopping an enzyme called PDE-5 from working as quickly, relaxing the blood vessels in the penis and increasing blood flow.

If you are sexually stimulated after taking Hezkue spray, you will be able to get an erection more easily, and it should last longer. Hezkue spray does not cause an erection on its own, you still need to be sexually aroused.

How long does Hezkue spray last?

Sildenafil can last around 4 to 5 hours after taking it, with most people still able to get an erection at this time. If you have tried it on 8 different occasions and it’s not working for as long as you would like, speak to your doctor. You can only use it once during the same 24 hour period.

How long does Hezkue spray take to work?

Further studies are needed into how long it takes for sildenafil to work when taken as a mouth spray. Current data for sildenafil tablets show that it can provide an erection good enough for sex in around 12 to 37 minutes, but it can take up to 1 hour.

Early studies into Hezkue spray, when taken as a 100mg dose, show it can be absorbed in as little as 5 to 20 minutes, but for now, it’s recommended to take it an hour before sex to make sure you’ve given it long enough to work.

How effective is the sildenafil spray?

Sildenafil works for around 74% of people who take it at the recommended 50mg dose and for 82% taking the 100mg dose. Research is still ongoing into the effectiveness of sildenafil as a mouth spray, but current trials show that it’s just as effective as its equivalent (Viagra and sildenafil tablets).

It may also work faster – Hezkue spray at a 100mg dose provides quicker absorption into the bloodstream than Viagra 100mg tablets within 20 minutes of taking it. More research is needed into this to confirm how quickly sildenafil spray works compared to tablets.

Take Hezkue spray around an hour before you want to have sex, as this will give it enough time to work. You will need to be sexually aroused to get an erection. You cannot take Hezkue spray more than once every 24 hours.

Dosage

The different dosages of Hezkue spray are:

Each press of the pump releases 0.5ml containing 12.5mg of sildenafil. Your dosage can be changed by your doctor, depending on how you react to the treatment.

Speak to your doctor if you take more Hezkue spray than you have been prescribed. You may get side effects, or they may be more severe.

Getting your bottle ready for use:

1. Shake the bottle for around 20 seconds to mix the medication.
2. Remove the cap by pressing down and twisting anticlockwise.
3. Attach the pump to the top of the bottle with the plastic tube sitting inside the bottle. Screw clockwise until attached.
4. When ready, turn the nozzle to the ‘open’ position so that medication can be released.
5. Before every use, pump 3 times to prime the bottle. Do not use any medication released during priming. This step is to make sure medication is coming out properly, so you will get the correct dose per spray.

Using Hezkue:

1. Tilt your head back and put the bottle next to your chin. Only ever spray Hezkue into your mouth.
2. Press down on the pump for your correct dosage (2 to 8 pumps). Spray the medication onto your tongue.
3. Swallow it straight away with saliva.

Storing the spray correctly between uses:

1. Turn the nozzle to ‘closed’ and remove the pump.
2. Tap the internal tube inside the bottle to remove any medication still inside.
3. Put the cap back on the bottle.
4. Wash the pump thoroughly with only water. After washing, press the pump a few times to make sure there is no water or medication left inside the small tube.
5. Allow the pump to dry thoroughly before you use it again.

Once the medication goes below the red line (on the bottom of the bottle), stop using Hezkue spray and discard it safely.

Important information

You can take sildenafil spray with or without food, but you do not need to drink anything to take it. Eating a heavy meal before taking it may affect how long it takes to work. Alcohol can also impact its effectiveness, as it temporarily reduces your ability to get an erection.

To get the maximum benefit from Hezkue spray, we recommend not drinking excessive amounts of alcohol while taking it.

Hezkue spray can cause some side effects, and how often these happen depends on each person. Speak to your doctor if your side effects are severe or ongoing.

Very commonly, Hezkue spray can cause headaches.

The common side effects of Hezkue spray include:

• dizziness
• feeling sick (nausea)
• stomach ache
• flushing
• nasal congestion
• visual disturbances or colour changes

These should get better as your body gets used to the treatment.

Uncommon side effects of Hezkue spray include:

• being sick (vomiting)
• low blood pressure
• muscle pain
• skin rash
• eye problems, including irritation, discharge, red eyes, and pain
• flashing lights, visual clarity, sensitivity to light, watery eyes
• palpitations
• high blood pressure
• fast heart rate
• drowsiness
• a reduced sensation of touch
• vertigo (extreme dizziness)
• ringing in the ears
• dry mouth
• blocked or congested sinuses
• inflammation of the lining of the nose
• gastroesophageal reflux disease (can cause heartburn symptoms)
• blood in urine
• nosebleed
• pain in arms or legs
• feeling hot
• tiredness

Rare side effects of Hezkue spray include:

• sudden decrease or loss of hearing
• feeling of irritability
• fainting
• dry nose, swelling inside the nose
• presence of blood in the semen
• bleeding from the penis
• stroke – this is a medical emergency, call 999
• heart attack – this is a medical emergency, call 999
• irregular heartbeat
• numbness in the mouth
• temporary decrease in blood flow to some parts of the brain
• bleeding in the back of the eye
• feeling of tightness in the throat
• changes to vision, such as double vision, small particles or spots in the vision, or decreased visual acuity
• abnormal sensation in the eye
• swelling of the eye or eyelid
• dilation of the eye pupil, change of colour of the whites of the eye
• vision of halos around lights

Serious side effects from Hezkue require immediate medical care. Call your GP or 111, and in an emergency go to A&E or call 999. These include:

• allergic reaction – symptoms include sudden wheezing, shortness of breath, dizziness, and swelling of the face, lips, or throat (call 999 straight away)
• chest pains – get into a semi-sitting position and try to relax, do not use nitrates, and contact your doctor straight away
• prolonged, painful erections – if you have an erection that lasts more than 4 hours, go to A&E or call 999
• a sudden decrease or loss of vision – if this happens, speak to your doctor straight away or call 999 in an emergency
• serious skin reactions – if you get symptoms like severe skin peeling and swelling, blisters, fever, or bumps on the genitals and around the eyes, call 999
• seizures or fits – if this happens, speak to your doctor straight away

Always read the patient information leaflet included with your medication before taking it.

How long do Hezkue spray side effects last?

Most Hezkue spray side effects should be short-lived, getting better within a few hours of taking it, but may come back when you use it again. Trying the medication a few different times may help your body get used to it, but if your side effects do not get better, last longer, or are severe, speak to a doctor or call 999 in an emergency.

What to do if you get Hezkue spray side effects

Some side effects of sildenafil spray can be managed at home. If they become severe or long-lasting, you should speak to a doctor. You can manage mild Hezkue side effects by:

• staying hydrated, which may also mean avoiding alcohol or making sure to drink water between alcoholic drinks – this can help, especially with headaches
• taking over-the-counter painkillers like paracetamol and ibuprofen – for things like headaches or pain
• avoiding strenuous activity – if you get side effects like dizziness, nausea, or vomiting, it’s best to rest until these side effects get better, which may mean postponing sex
• making sure you’ve eaten a light meal or snack before taking it – this may help with things like dizziness, stomach ache, and nausea, which may get worse if you take Hezkue on an empty stomach
• keeping the room cool – this can help with flushing and dizziness
• only taking the dose you’ve been prescribed and never more than once in 24 hours – taking it more can cause side effects or make the ones you already get more severe

Hezkue may not be right for everyone – certain health conditions or other medications can interact with sildenafil spray and make it less effective, or potentially unsafe. You should always tell your prescribing doctor about any medications you’re taking and any conditions you have, or are being investigated for.

You should not take Hezkue if you:

• are a woman or are under the age of 18
• do not have ED
• have ever had an allergic reaction to sildenafil or any other ingredients in the spray
• have a severe heart or liver problem
• have recently had a stroke or a heart attack
• have low blood pressure
• have certain eye diseases, such as retinitis pigmentosa, or have ever lost your vision because of non-arteritic anterior ischaemic optic neuropathy (NAION)
• are taking any other ED treatments or medications that contain a PDE-5 inhibitor like sildenafil

Let your doctor know before taking Hezkue if you have:

• heart problems
• sickle cell anaemia
• leukaemia or multiple myeloma (types of cancer)
• a deformity of your penis or Peyronie’s Disease
• a stomach ulcer, or a bleeding problem
• kidney or liver problems – you may need a lower dose

Some medications should not be taken with Hezkue, such as:

• nitrates for chest pain or angina, or nitric oxide donors, such as amyl nitrite (poppers) – taking sildenafil with either of these may lead to a dangerous drop in blood pressure
• riociguat, a medication used for high blood pressure in the lungs – taking sildenafil spray at the same time may increase the effects of this medication, which can be unsafe

Let your doctor know about any other medications, especially if you are taking:

• protease inhibitors, such as for the treatment of HIV – you may need to start on a lower dose
• alpha-blocker therapy for high blood pressure or prostate enlargement – you may be more likely to get dizziness or light-headedness
• sacubitril/valsartan, used to treat heart failure

Hezkue spray can be prescribed by private prescribers, such as Asda Online Doctor, and may be available at some pharmacies.

Can I buy sildenafil spray online?

Yes, you can get sildenafil spray (Hezkue spray) online after being prescribed it. To get your ED treatment from us, you can:

1. Fill out a short consultation with pre-filled questions, letting us know your symptoms and any medications you’re taking that could affect your ability to get sildenafil spray.
2. One of our doctors will check your consultation and can prescribe treatment if it’s safe and suitable for you.
3. During check out, you will have chosen either discreet home delivery or Click & Collect from your chosen Asda Pharmacy. We’ll let you know when your order will be ready or when it’s being delivered.
4. If you have further questions after receiving your treatment, you can message a doctor for free through your online account.

Our ED service is quick and easy to use, and allows you to get ED treatment without a face-to-face appointment, which can be beneficial if you do not have time or would prefer not to speak to a doctor in person. We have a range of treatments available, so if Hezkue spray is not suitable, we may be able to offer an alternative.

Can I buy Hezkue spray over the counter?

No, Hezkue spray is a prescription only medication containing sildenafil, and a doctor must check it's suitable for you to use. You can get Viagra Connect over the counter, which contains 50mg of sildenafil, but a pharmacist will still need to complete a quick consultation with you.

Can I get Hezkue on the NHS?

No, Hezkue is not currently available on the NHS and is only available through private prescribers. It’s a new medication in the UK as of early 2025, so NHS availability may change in the future.

Hezkue spray has a few alternatives, but there are no other ED mouth sprays available. Alternatives to Hezkue include tablets containing the same active ingredient, other PDE-5 tablets, or a cream called Vitaros.

Other ED treatments available at Asda online doctor include:

• sildenafil, a generic tablet alternative to Hezkue with the same doses, working in the same way
• Viagra, a branded tablet alternative with the same doses, also works in the same way but at a higher price than generic sildenafil tablets
• Viagra Connect, an over-the-counter Hezkue alternative also containing sildenafil, but only in 50mg tablets
• tadalafil, a generic, different type of PDE-5 tablet, still works in the same way as Hezkue but can last up to 36 hours instead
• Cialis, the branded version of tadalafil, working in the same way
• Spedra, a branded PDE-5 tablet that works like Hezkue, but works faster than other sildenafil tablets, as it can work in 20 minutes
• vardenafil, a generic PDE-5 tablet that takes around the same time to work as sildenafil and lasts just as long, may be a suitable alternative if you cannot take sildenafil
• Vitaros cream, a cream inserted into the penis to provide an erection in as little as 5 minutes, containing a medication called alprostadil, which also improves blood flow by relaxing blood vessels

Hezkue spray and Viagra are similar as they contain the same active ingredient but come in a different form:

Tadalafil is different from Hezkue spray as it contains a different active ingredient and lasts longer. Tadalafil is also available at a lower daily dose for people who have sex often (more than 3 times a week):

Hezkue and vardenafil are similar in that they last around the same time, but they contain different active ingredients and come in different forms: